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It was held to be incontrovertible evidence of the efficacy of the remedy, that, in those cases where the sensible effects of mercury took place, recovery usually followed; and although the mortality under thse new treatment continued to be excessive, yet as the greater number with ptyalisra recovered, the failures were not permitted to affect the reputation of the It is probable, that the observation of the fact of the salivary glands being unintentionally affected, in some cases of recovery, by the eye calomel combined with the purgatives, may have led to the inference that the declension of fever was the effect of the salivation, whereas the converse of the conclusion is the truth; for, although the two events may appear to be synchronous, yet, as experience proves, that all attempts to excite the specific action of mercury in a system labouring under a high degree of fever are perfectly unavailing, until the fever be moderated by other means, we are justified in concluding, that the declension of fever, and the supervention of salivation, stand in the relation of cause and The coexistence of febrile and mercurial action is generally admitted to be incompatible; if therefore the action of mercury could be superinduced in violent fever, we should be possessed of an invaluable remedy; but in a high degree of fever we find mercury to be utterly powerless, in whatever quantity or manner it may he exhibited; and if exclusively confided in, the disease pursues its march unchecked, to disorganization and death, without the appearance of any sensible effect from the mercury employed. If the uk patient becomes pregnant while taking this class of drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus.

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