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And their toxines, and the dystrophy consecutive to obliteration of the vessels, affect the fixed cells of the tissue and the leucocytes, which have accumulated there in numbers, causing granulo-fatty and vitreous degeneration, followed by necrosis and ulceration: app. Impetigo vulgaris, the variety most frequently observed among children and often termed impetigo contagiosa, begins as a streptococcic infection; the typical bulla of that form becoming puru'ent.

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